Welcome to the homepage of the Titov Lab. Our laboratory is based in the Departments of Molecular & Cell Biology, Nutritional Sciences & Toxicology, and the Center for Computational Biology at the University of California, Berkeley.
The long-term goal of our laboratory is to understand the molecular basis of inactivation of cellular machinery during aging. We are interested in addressing the following broad questions: What are the cellular processes whose inactivation determines the lifespan of different organisms? What are the molecular mechanisms of age-associated damage to proteins, nucleic acids and lipids? How do environmental and genetic factors modulate the rate of aging?
In order to tackle these questions we are using a combination of biochemistry, physiology, mathematical modeling, custom instrumentation and novel tool development to study aging in cell culture and model organisms.